Blar i forfatter "Hössjer, Ola"

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    • Estimating the information content of genetic sequence data 

      Thorvaldsen, Steinar; Hössjer, Ola (Journal article; Tidsskriftartikkel, 2023-07-25)
      A prominent problem in analysing genetic information has been a lack of mathematical frameworks for doing so. This article offers some new statistical methods to model and analyse information content in proteins, protein families, and their sequences. We discuss how to understand the qualitative aspects of genetic information, how to estimate the quantitative aspects of it, and implement a statistical ...

    • Using statistical methods to model the fine-tuning of molecular machines and systems 

      Thorvaldsen, Steinar; Hössjer, Ola (Journal article; Tidsskriftartikkel, 2020-06-04)
      Fine-tuning has received much attention in physics, and it states that the fundamental constants of physics are finely tuned to precise values for a rich chemistry and life permittance. It has not yet been applied in a broad manner to molecular biology. However, in this paper we argue that biological systems present fine-tuning at different levels, e.g. functional proteins, complex biochemical ...